Acting locally but sensing globally: impact of GABAergic synaptic plasticity on phasic and tonic inhibition in the thalamus

We have discovered that adult thalamocortical relay neurones exhibit a sustained enhancement of synaptic inhibition triggered by transient action potential firing of a single thalamic relay neurone. The sustained activity-dependent increase in IPSC frequency (+48.3 ± 11.4%, n = 32) was blocked by ch...

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Autores principales: Bright, Damian P, Brickley, Stephen G
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2008
Materias:
Rapid Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652165/
https://ncbi.nlm.nih.gov/pubmed/18772202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.158576
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