Auto-Ubiquitination-Induced Degradation of MALT1-API2 Prevents BCL10 Destabilization in t(11;18)(q21;q21)-Positive MALT Lymphoma

BACKGROUND: The translocation t(11;18)(q21;q21) is the most frequent chromosomal aberration associated with MALT lymphoma and results in constitutive NF-κB activity via the expression of an API2-MALT1 fusion protein. The properties of the reciprocal MALT1-API2 were never investigated as it was repor...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Noels, Heidi, Somers, Riet, Liu, Hongxiang, Ye, Hongtao, Du, Ming-Qing, De Wolf-Peeters, Christiane, Marynen, Peter, Baens, Mathijs
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652110/
https://ncbi.nlm.nih.gov/pubmed/19279678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004822
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы