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Hypoxia associated p38 Mitogen Activated Protein Kinase Mediated Androgen Receptor Activation and Increased Hif-1α Levels Contribute to emergence of an Aggressive Phenotype in Prostate Cancer

Androgen Receptor (AR) -signaling plays a critical role in the development and progression of prostate cancer. Tumor microvasculature contributes to continual exposure of prostate cancer cells to hypoxia-reoxygenation, however, the role of hypoxia-reoxygenation in prostate cancer progression and mod...

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Autors principals: Khandrika, Lakshmipathi, Lieberman, Rachel, Koul, Sweaty, Kumar, Binod, Maroni, Paul, Chandhoke, Ryan, Meacham, Randall B, Koul, Hari K
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651999/
https://ncbi.nlm.nih.gov/pubmed/19151763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.476
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