Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

BACKGROUND: β-cells are extremely rich in zinc and zinc homeostasis is regulated by zinc transporter proteins. β-cells are sensitive to cytokines, interleukin-1β (IL-1β) has been associated with β-cell dysfunction and -death in both type 1 and type 2 diabetes. This study explores the regulation of z...

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Autors principals: Egefjord, Lærke, Jensen, Jens Ledet, Bang-Berthelsen, Claus Heiner, Petersen, Andreas Brønden, Smidt, Kamille, Schmitz, Ole, Karlsen, Allan Ertman, Pociot, Flemming, Chimienti, Fabrice, Rungby, Jørgen, Magnusson, Nils E
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651882/
https://ncbi.nlm.nih.gov/pubmed/19243577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6823-9-7
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