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PANCREATIC REG I BINDS MKP-1 AND REGULATES CYCLIN D IN PANCREATIC-DERIVED CELLS

BACKGROUND: The pancreatic regenerating (reg I) gene and its protein product are derived from acinar cells, and are mitogenic to β- and ductal cells. We studied the mechanism of this mitogenic response. METHODS: ARIP (rat ductal) and RIN 1046–38 (rat β-) cell lines were exposed to exogenous reg I in...

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Detalhes bibliográficos
Main Authors: Mueller, Cathy M., Zhang, Hong, Zenilman, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651821/
https://ncbi.nlm.nih.gov/pubmed/18929742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.03.047
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