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Deficiency of the tRNA(Tyr):Ψ35-synthase aPus7 in Archaea of the Sulfolobales order might be rescued by the H/ACA sRNA-guided machinery

Up to now, Ψ formation in tRNAs was found to be catalysed by stand-alone enzymes. By computational analysis of archaeal genomes we detected putative H/ACA sRNAs, in four Sulfolobales species and in Aeropyrum pernix, that might guide Ψ35 formation in pre-tRNA(Tyr)(GUA). This modification is achieved...

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Detalhes bibliográficos
Main Authors: Muller, Sébastien, Urban, Alan, Hecker, Arnaud, Leclerc, Fabrice, Branlant, Christiane, Motorin, Yuri
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651775/
https://ncbi.nlm.nih.gov/pubmed/19139072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1037
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