Mutational Analysis and Allosteric Effects in the HIV-1 Capsid Protein Carboxyl-Terminal Dimerization Domain

[Image: see text] The carboxyl-terminal domain (CTD, residues 146−231) of the HIV-1 capsid (CA) protein plays an important role in the CA−CA dimerization and viral assembly of the human immunodeficiency virus type 1. Disrupting the native conformation of the CA is essential for blocking viral capsid...

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Detalhes bibliográficos
Main Authors: Yu, Xiang, Wang, Qiuming, Yang, Jui-Chen, Buch, Idit, Tsai, Chung-Jung, Ma, Buyong, Cheng, Stephen Z. D., Nussinov, Ruth, Zheng, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2009
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651736/
https://ncbi.nlm.nih.gov/pubmed/19199580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm801151r
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