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Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development
Congenital heart disease is the most common type of birth defect with an incidence of 1%. Previously, we described a point mutation in GATA4 that segregated with cardiac defects in a family with autosomal dominant disease. The mutation (G296S) exhibited biochemical deficits and disrupted a novel int...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651674/ https://ncbi.nlm.nih.gov/pubmed/19084512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.11.004 |
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