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A Peptide Targeted Contrast Agent Specific to Fibrin-Fibronectin Complexes for Cancer Molecular Imaging with MRI
[Image: see text] A peptide targeted contrast agent, CLT1-(Gd-DTPA), was synthesized for molecular imaging of fibronectin−fibrin complexes in tumor tissue with magnetic resonance imaging (MRI). The T(1) and T(2) relaxivities of CLT1-(Gd-DTPA) were 4.22 and 4.45 mM(−1) s(−1) at 3 T, respectively. The...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2008
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2651601/ https://ncbi.nlm.nih.gov/pubmed/19053180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800211r |
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