Core-Shell Hydrogel Particles Harvest, Concentrate and Preserve Labile Low Abundance Biomarkers

BACKGROUND: The blood proteome is thought to represent a rich source of biomarkers for early stage disease detection. Nevertheless, three major challenges have hindered biomarker discovery: a) candidate biomarkers exist at extremely low concentrations in blood; b) high abundance resident proteins su...

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Detalhes bibliográficos
Main Authors: Longo, Caterina, Patanarut, Alexis, George, Tony, Bishop, Barney, Zhou, Weidong, Fredolini, Claudia, Ross, Mark M., Espina, Virginia, Pellacani, Giovanni, Petricoin, Emanuel F., Liotta, Lance A., Luchini, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651577/
https://ncbi.nlm.nih.gov/pubmed/19274087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004763
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