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A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

An intriguing question in human embryonic stem cell (hESC) biology is whether these pluripotent cells can give rise to stably expandable somatic stem cells, which are still amenable to extrinsic fate instruction. Here, we present a pure population of long-term self-renewing rosette-type hESC-derived...

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Detalhes bibliográficos
Main Authors: Koch, Philipp, Opitz, Thoralf, Steinbeck, Julius A., Ladewig, Julia, Brüstle, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651316/
https://ncbi.nlm.nih.gov/pubmed/19218428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808387106
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