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Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest

Several arenaviruses cause hemorrhagic fever disease in humans for which no licensed vaccines are available and current therapeutic intervention is limited to the off-label use of the wide-spectrum antiviral ribavirin. However, the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) has...

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Detalhes bibliográficos
Main Authors: Emonet, Sebastien F., Garidou, Lucile, McGavern, Dorian B., de la Torre, Juan C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651270/
https://ncbi.nlm.nih.gov/pubmed/19208813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900088106
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