Identification of a Plasmodium falciparum intercellular adhesion molecule-1 binding domain: A parasite adhesion trait implicated in cerebral malaria

Binding of infected erythrocytes to brain venules is a central pathogenic event in the lethal malaria disease complication, cerebral malaria. The only parasite adhesion trait linked to cerebral sequestration is binding to intercellular adhesion molecule-1 (ICAM-1). In this report, we show that Plasm...

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Main Authors: Smith, Joseph D., Craig, Alister G., Kriek, Neline, Hudson-Taylor, Diana, Kyes, Sue, Fagen, Toby, Pinches, Robert, Baruch, Dror I., Newbold, Chris I., Miller, Louis H.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26510/
https://ncbi.nlm.nih.gov/pubmed/10677532
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