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Inhibition of Bacterial Ribosome Assembly: a Suitable Drug Target?

Summary: The assembly of bacterial ribosomes is viewed with increasing interest as a potential target for new antibiotics. The in vivo synthesis and assembly of ribosomes are briefly reviewed here, highlighting the many ways in which assembly can be perturbed. The process is compared with the model...

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Détails bibliographiques
Auteur principal: Maguire, Bruce A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650890/
https://ncbi.nlm.nih.gov/pubmed/19258531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.00030-08
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