A Common and Unstable Copy Number Variant Is Associated with Differences in Glo1 Expression and Anxiety-Like Behavior

Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ∼475 kb tandem duplication on chromosome 17 that incl...

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Detalhes bibliográficos
Main Authors: Williams, Richard, Lim, Jackie E., Harr, Bettina, Wing, Claudia, Walters, Ryan, Distler, Margaret G., Teschke, Meike, Wu, Chunlei, Wiltshire, Tim, Su, Andrew I., Sokoloff, Greta, Tarantino, Lisa M., Borevitz, Justin O., Palmer, Abraham A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650792/
https://ncbi.nlm.nih.gov/pubmed/19266052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004649
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