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ABCD of the phosphodiesterase family: interaction and differential activity in COPD

Phosphodiesterases (PDEs) are important enzymes that hydrolyze the cyclic nucleotides adenosine 3′5′-cyclic monophosphate (cAMP) and guanosine 3′5′-cyclic mono-phosphate (cGMP) to their inactive 5′ monophosphates. They are highly conserved across species and as well as their role in signal terminati...

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Detalhes bibliográficos
Autor principal: Halpin, David MG
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650605/
https://ncbi.nlm.nih.gov/pubmed/19281073
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