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Population Pharmacokinetic Analysis of Ceftobiprole for Treatment of Complicated Skin and Skin Structure Infections

Population pharmacokinetic analysis demonstrated that renal function, as assessed by creatinine clearance (CL(CR)), was the patient characteristic that had a clinically relevant impact on ceftobiprole pharmacodynamics. Dosing adjustments based on CL(CR) for subjects with renal impairment should prov...

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Detalhes bibliográficos
Main Authors: Kimko, Holly, Murthy, Bindu, Xu, Xu, Nandy, Partha, Strauss, Richard, Noel, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650522/
https://ncbi.nlm.nih.gov/pubmed/19075059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00632-08
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