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Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

Autophagy is a highly conserved process that maintains homeostasis by clearing damaged organelles and long-lived proteins. The consequences of deficiency in autophagy manifest in a variety of pathological states including neurodegenerative diseases, inflammatory disorders, and cancer. Here, we studi...

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Detalhes bibliográficos
Main Authors: Tal, Michal Caspi, Sasai, Miwa, Lee, Heung Kyu, Yordy, Brian, Shadel, Gerald S., Iwasaki, Akiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650341/
https://ncbi.nlm.nih.gov/pubmed/19196953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807694106
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