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Sialylated multivalent antigens engage CD22 in trans and inhibit B cell activation
CD22 is an inhibitory coreceptor on the surface of B cells that attenuates B cell antigen receptor (BCR) signaling and, therefore, B cell activation. Elucidating the molecular mechanisms underlying the inhibitory activity of CD22 is complicated by the ubiquity of CD22 ligands. Although antigens can...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650292/ https://ncbi.nlm.nih.gov/pubmed/19202057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807207106 |
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