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FGF-dependent left–right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1

Establishment of left–right asymmetry in vertebrates requires nodal, Wnt-PCP and FGF signaling and involves ciliogenesis in a laterality organ. Effector genes through which FGF signaling affects laterality have not been described. We isolated the zebrafish ier2 and fibp1 genes as FGF target genes an...

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Detalhes bibliográficos
Main Authors: Hong, Sung-Kook, Dawid, Igor B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650137/
https://ncbi.nlm.nih.gov/pubmed/19164561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812880106
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