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Optimization of labile esters for esterase–assisted accumulation of nitroxides into cells: A model for in vivo EPR imaging
Nitroxide–based electron paramagnetic resonance (EPR) imaging agents are useful quantitative probes of O(2) concentration in vivo in real time. Lipophilic, labile alkanoyloxymethyl esters of nitroxides can cross the blood-brain barrier, and after hydrolysis, the corresponding anionic nitroxide is in...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650013/ https://ncbi.nlm.nih.gov/pubmed/18783260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc8001562 |
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