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Rosiglitazone: can meta-analysis accurately estimate excess cardiovascular risk given the available data? Re-analysis of randomized trials using various methodologic approaches

BACKGROUND: A recent and provocative meta-analysis, based on few outcome events, suggested that rosiglitazone increased cardiovascular mortality and myocardial infarction. However, results of meta-analyses of trials with sparse events, often performed when examining uncommon adverse effects due to c...

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Detalhes bibliográficos
Main Authors: Friedrich, Jan O, Beyene, Joseph, Adhikari, Neill KJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649945/
https://ncbi.nlm.nih.gov/pubmed/19134216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-2-5
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