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Accumulation and dissemination of prion protein in experimental sheep scrapie in the natural host

BACKGROUND: In order to study the sites of uptake and mechanisms of dissemination of scrapie prions in the natural host under controlled conditions, lambs aged 14 days and homozygous for the VRQ allele of the PrP gene were infected by the oral route. Infection occurred in all lambs with a remarkably...

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Main Authors: Ryder, Stephen J, Dexter, Glenda E, Heasman, Lindsay, Warner, Richard, Moore, S Jo
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649917/
https://ncbi.nlm.nih.gov/pubmed/19243608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-6148-5-9
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