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Tamoxifen mediated estrogen receptor activation protects against early impairment of hippocampal neuron excitability in an oxygen/glucose deprivation brain slice ischemia model

Pretreatment of ovarectomized rats with estrogen shows long-term protection via activation of the estrogen receptor (ER). However, it remains unknown whether activation of the ER can provide protection against early neuronal damage when given acutely, we simulated ischemic conditions by applying oxy...

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Main Authors: Zhang, Huaqiu, Xie, Minjie, Schools, Gary P., Feustel, Paul F., Wang, Wei, Lei, Ting, Kimelberg, Harold K., Zhou, Min
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649761/
https://ncbi.nlm.nih.gov/pubmed/18992727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.10.015
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