Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study

BACKGROUND: We hypothesized that the addition of sirolimus to standard horse antithymocyte globulin (h-ATG) and cyclosporine (CsA) would improve response rates in severe aplastic anemia, due to its complementary and synergistic properties to cyclosporine A. DESIGN AND METHODS: To test this hypothesi...

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Autors principals: Scheinberg, Phillip, Wu, Colin O., Nunez, Olga, Scheinberg, Priscila, Boss, Carol, Sloand, Elaine M., Young, Neal S.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2009
Matèries:
Aplastic Anemia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649367/
https://ncbi.nlm.nih.gov/pubmed/19181786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.13829
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