Comparative analysis of oncogenic properties and nuclear factor-κB activity of latent membrane protein 1 natural variants from Hodgkin’s lymphoma’s Reed-Sternberg cells and normal B-lymphocytes

BACKGROUND: In Epstein-Barr virus-associated Hodgkin’s lymphomas, neoplastic Reed-Sternberg cells and surrounding non-tumor B-cells contain different variants of the LMP1-BNLF1 oncogene. In this study, we raised the question of functional properties of latent membrane protein 1 (LMP1) natural varian...

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Main Authors: Faumont, Nathalie, Chanut, Aurélie, Benard, Alan, Cogne, Nadine, Delsol, Georges, Feuillard, Jean, Meggetto, Fabienne
Formáid: Artigo
Teanga:Inglês
Foilsithe: Ferrata Storti Foundation 2009
Ábhair:
Hodgkin's Lymphoma
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649341/
https://ncbi.nlm.nih.gov/pubmed/19211641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.13269
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