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The functional relationships underlying a synthetic genetic network

Here, we focus on synthetic lethal genetic interactions, examples of genetic enhancements, where mutations in two different genes result in lethality but only when present together. We recently identified the synthetic lethal network around the PKC1 gene encoding the essential protein kinase C of ye...

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Detalhes bibliográficos
Main Authors: Krause, Sue A, Gray, Joseph V
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649287/
https://ncbi.nlm.nih.gov/pubmed/19704853
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