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The poly(A)-dependent degradation pathway of rpsO mRNA is primarily mediated by RNase R

Polyadenylation is an important factor controlling RNA degradation and RNA quality control mechanisms. In this report we demonstrate for the first time that RNase R has in vivo affinity for polyadenylated RNA and can be a key enzyme involved in poly(A) metabolism. RNase II and PNPase, two major RNA...

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Detalhes bibliográficos
Main Authors: Andrade, José M., Hajnsdorf, Eliane, Régnier, Philippe, Arraiano, Cecília M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648712/
https://ncbi.nlm.nih.gov/pubmed/19103951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1197309
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