A Sphingosine-1–Phosphate–Activated Calcium Channel Controlling Vascular Smooth Muscle Cell Motility

In a screen of potential lipid regulators of transient receptor potential (TRP) channels, we identified sphingosine-1–phosphate (S1P) as an activator of TRPC5. We explored the relevance to vascular biology because S1P is a key cardiovascular signaling molecule. TRPC5 is expressed in smooth muscle ce...

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Autori principali: Xu, Shang-Zhong, Muraki, Katsuhiko, Zeng, Fanning, Li, Jing, Sukumar, Piruthivi, Shah, Samir, Dedman, Alexandra M., Flemming, Philippa K., McHugh, Damian, Naylor, Jacqueline, Cheong, Alex, Bateson, Alan N., Munsch, Christopher M., Porter, Karen E., Beech, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648505/
https://ncbi.nlm.nih.gov/pubmed/16675717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000225284.36490.a2
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