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The Rcs Two-Component System Regulates Expression of Lysozyme Inhibitors and Is Induced by Exposure to Lysozyme

The Escherichia coli Rcs regulon is triggered by antibiotic-mediated peptidoglycan stress and encodes two lysozyme inhibitors, Ivy and MliC. We report activation of this pathway by lysozyme and increased lysozyme sensitivity when Rcs induction is genetically blocked. This lysozyme sensitivity could...

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Main Authors: Callewaert, Lien, Vanoirbeek, Kristof G. A., Lurquin, Ine, Michiels, Chris W., Aertsen, Abram
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648352/
https://ncbi.nlm.nih.gov/pubmed/19136591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01549-08
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