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A Systems Biology Approach To Identify the Combination Effects of Human Herpesvirus 8 Genes on NF-κB Activation

Human herpesvirus 8 (HHV-8) is the etiologic agent of Kaposi's sarcoma and primary effusion lymphoma. Activation of the cellular transcription factor nuclear factor-kappa B (NF-κB) is essential for latent persistence of HHV-8, survival of HHV-8-infected cells, and disease progression. We used r...

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Bibliographische Detailangaben
Hauptverfasser: Konrad, Andreas, Wies, Effi, Thurau, Mathias, Marquardt, Gaby, Naschberger, Elisabeth, Hentschel, Sonja, Jochmann, Ramona, Schulz, Thomas F., Erfle, Holger, Brors, Benedikt, Lausen, Berthold, Neipel, Frank, Stürzl, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648262/
https://ncbi.nlm.nih.gov/pubmed/19129458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01512-08
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