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Inhibition of the Ubiquitin-Proteasome System Prevents Vaccinia Virus DNA Replication and Expression of Intermediate and Late Genes

The ubiquitin-proteasome system has a central role in the degradation of intracellular proteins and regulates a variety of functions. Viruses belonging to several different families utilize or modulate the system for their advantage. Here we showed that the proteasome inhibitors MG132 and epoxomicin...

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Detalhes bibliográficos
Main Authors: Satheshkumar, P. S., Anton, Luis C., Sanz, Patrick, Moss, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648259/
https://ncbi.nlm.nih.gov/pubmed/19129442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01986-08
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