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RNA-Regulated Interaction of Transportin-1 and Exportin-5 with the Double-Stranded RNA-Binding Domain Regulates Nucleocytoplasmic Shuttling of ADAR1

Double-stranded RNA (dsRNA)-binding proteins interact with substrate RNAs via dsRNA-binding domains (dsRBDs). Several proteins harboring these domains exhibit nucleocytoplasmic shuttling and possibly remain associated with their substrate RNAs bound in the nucleus during nuclear export. In the human...

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Autors principals: Fritz, Jutta, Strehblow, Alexander, Taschner, Andreas, Schopoff, Sandy, Pasierbek, Pawel, Jantsch, Michael F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648229/
https://ncbi.nlm.nih.gov/pubmed/19124606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01519-08
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