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Novel Cell-Based Method To Detect Shiga Toxin 2 from Escherichia coli O157:H7 and Inhibitors of Toxin Activity

Escherichia coli O157:H7 is a leading cause of food-borne illness. This human pathogen produces Shiga toxins (Stx1 and Stx2) which inhibit protein synthesis by inactivating ribosome function. The present study describes a novel cell-based assay to detect Stx2 and inhibitors of toxin activity. A Vero...

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Detalhes bibliográficos
Main Authors: Quiñones, Beatriz, Massey, Shane, Friedman, Mendel, Swimley, Michelle S., Teter, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648150/
https://ncbi.nlm.nih.gov/pubmed/19139230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02230-08
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