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Simvastatin induces cell death in a mouse cerebellar slice culture (CSC) model of developmental myelination
Statins (inhibitors of HMG-CoA reductase) have shown promise in treating multiple sclerosis (MS). However, their effect on oligodendrocyte remyelination of demyelinated axons has not been clarified. Since developmental myelination shares many features with the remyelination process, we investigated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647813/ https://ncbi.nlm.nih.gov/pubmed/18929563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2008.09.010 |
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