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Mef2-mediated transcription of the miR379–410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels

Neuronal activity orchestrates the proper development of the neuronal circuitry by regulating both transcriptional and post-transcriptional gene expression programmes. How these programmes are coordinated, however, is largely unknown. We found that the transcription of miR379–410, a large cluster of...

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Hlavní autoři: Fiore, Roberto, Khudayberdiev, Sharof, Christensen, Mette, Siegel, Gabriele, Flavell, Steven W, Kim, Tae-Kyung, Greenberg, Michael E, Schratt, Gerhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647767/
https://ncbi.nlm.nih.gov/pubmed/19197241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.10
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