Ligand-engaged urokinase-type plasminogen activator receptor and activation of the CD11b/CD18 integrin inhibit late events of HIV expression in monocytic cells

Urokinase-type plasminogen activator (uPA) signaling via its receptor uPAR inhibits late events in HIV-1 replication in acutely infected primary monocyte-derived macrophages (MDMs) and promonocytic U937 cells. Here we show that U937-derived, chronically infected U1 cells stimulated with phorbol 12-m...

Full description

Saved in:
Bibliographic Details
Main Authors: Alfano, Massimo, Mariani, Samanta A., Elia, Chiara, Pardi, Ruggero, Blasi, Francesco, Poli, Guido
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647677/
https://ncbi.nlm.nih.gov/pubmed/18941116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-138412
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items