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Glutamate and dopamine components in schizophrenia

The treatment of schizophrenia for the last half century has been with dopamine (DA) D(2) receptor blockers, implicating a hyperdopamine basis for psychosis. However, a 2007 report found that the glutamate agonist LY404039 was effective in schizophrenia, suggesting a hypoglutamate state for the illn...

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Detalles Bibliográficos
Autor Principal: Seeman, Philip
Formato: Artigo
Idioma:Inglês
Publicado: Canadian Medical Association 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647567/
https://ncbi.nlm.nih.gov/pubmed/19270765
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