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Three-dimensional structure of the human copper transporter hCTR1

Copper uptake proteins (CTRs), mediate cellular acquisition of the essential metal copper in all eukaryotes. Here, we report the structure of the human CTR1 protein solved by electron crystallography to an in plane resolution of 7 Å. Reminiscent of the design of traditional ion channels, trimeric hC...

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Autors principals: De Feo, Christopher J., Aller, Stephen G., Siluvai, Gnana S., Blackburn, Ninian J., Unger, Vinzenz M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647337/
https://ncbi.nlm.nih.gov/pubmed/19240214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810286106
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