A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference

Anti-miRNA antisense inhibitors (AMOs) have demonstrated their utility in miRNA research and potential in miRNA therapy. Here we report a modified AMO approach in which multiple antisense units are engineered into a single unit that is able to simultaneously silence multiple-target miRNAs, the multi...

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Bibliographic Details
Main Authors: Lu, Yanjie, Xiao, Jiening, Lin, Huixian, Bai, Yunlong, Luo, Xiaobin, Wang, Zhiguo, Yang, Baofeng
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Methods Online
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647303/
https://ncbi.nlm.nih.gov/pubmed/19136465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1053
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