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Reactive oxygen species regulate DNA copy number in isolated yeast mitochondria by triggering recombination-mediated replication
Mitochondrial DNA (mtDNA) encodes proteins that are essential for cellular ATP production. Reactive oxygen species (ROS) are respiratory byproducts that damage mtDNA and other cellular components. In Saccharomyces cerevisiae, the oxidized base excision-repair enzyme Ntg1 introduces a double-stranded...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647299/ https://ncbi.nlm.nih.gov/pubmed/19074198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn993 |
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