Targeting Myelin Proteolipid Protein to the MHC Class I Pathway by Ubiquitination Modulates the Course of Experimental Autoimmune Encephalomyelitis

Relapsing-remitting experimental autoimmune encephalomyelitis (EAE), a multiple sclerosis model, is induced in mice by injection of myelin proteolipid protein (PLP) encephalitogenic peptide, PLP(139–151), in adjuvant. In this study, prior to EAE induction, mice were vaccinated with a bacterial plasm...

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Bibliographic Details
Main Authors: Theil, Diethilde J., Libbey, Jane E., Rodriguez, Fernando, Whitton, J. Lindsay, Tsunoda, Ikuo, Derfuss, Tobias J., Fujinami, Robert S.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646907/
https://ncbi.nlm.nih.gov/pubmed/18706703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.07.005
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