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Decreased NO signaling leads to enhanced vasoconstrictor responsiveness in skeletal muscle arterioles of the ZDF rat prior to overt diabetes and hypertension

Approximately 40% of patients with type 2 diabetes present with concurrent hypertension at the time of diabetes diagnosis. Increases in peripheral vascular resistance and correspondingly enhanced vasoconstrictor capacity could have profound implications for the development of hypertension and the pr...

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Détails bibliographiques
Auteurs principaux: Lesniewski, Lisa A., Donato, Anthony J., Behnke, Bradley J., Woodman, Christopher R., Laughlin, M. Harold, Ray, Chester A., Delp, Michael D.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646849/
https://ncbi.nlm.nih.gov/pubmed/18245568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00692.2007
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