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Escherichia coli MazF Leads to the Simultaneous Selective Synthesis of Both “Death Proteins” and “Survival Proteins”

The Escherichia coli mazEF module is one of the most thoroughly studied toxin–antitoxin systems. mazF encodes a stable toxin, MazF, and mazE encodes a labile antitoxin, MazE, which prevents the lethal effect of MazF. MazF is an endoribonuclease that leads to the inhibition of protein synthesis by cl...

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Bibliografiske detaljer
Main Authors: Amitai, Shahar, Kolodkin-Gal, Ilana, Hananya-Meltabashi, Mirit, Sacher, Ayelet, Engelberg-Kulka, Hanna
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646832/
https://ncbi.nlm.nih.gov/pubmed/19282968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000390
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