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An Allelic Exchange System for Compliant Genetic Manipulation of the Select Agents Burkholderia pseudomallei and Burkholderia mallei

Burkholderia pseudomallei and B. mallei are Gram-negative bacterial pathogens that cause melioidosis in humans and glanders in horses, respectively. Both bacteria are classified as category B select agents in the United States. Due to strict select-agent regulations, the number of antibiotic selecti...

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Autors principals: Hamad, Mohamad A., Zajdowicz, Sheryl L., Holmes, Randall K., Voskuil, Martin I.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646673/
https://ncbi.nlm.nih.gov/pubmed/19010402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.10.011
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