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An update on the toxicity of Aβ in Alzheimer’s disease

Alzheimer’s disease is characterized histopathologically by deposition of insoluble forms of the peptide Aβ and the protein tau in brain. Aβ is the principal component of amyloid plaques and tau of neurofibrillary tangles. Familial cases of AD are associated with causal mutations in the gene encodin...

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Detalhes bibliográficos
Main Authors: Götz, Jürgen, Ittner, Lars M, Schonrock, Nicole, Cappai, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646638/
https://ncbi.nlm.nih.gov/pubmed/19337449
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