Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, debilitating respiratory disease whose pathogenesis is poorly understood. In IPF, the lung parenchyma undergoes extensive remodeling. We hypothesized that lymphangiogenesis is part of lung remodeling and sought to characterize pathways l...

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Main Authors: El-Chemaly, Souheil, Malide, Daniela, Zudaire, Enrique, Ikeda, Yoshihiko, Weinberg, Benjamin A., Pacheco-Rodriguez, Gustavo, Rosas, Ivan O., Aparicio, Marta, Ren, Ping, MacDonald, Sandra D., Wu, Hai-Ping, Nathan, Steven D., Cuttitta, Frank, McCoy, J. Philip, Gochuico, Bernadette R., Moss, Joel
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646625/
https://ncbi.nlm.nih.gov/pubmed/19237567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813368106
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