Opposing Effects of Platelet-Activating Factor and Lyso-Platelet-Activating Factor on Neutrophil and Platelet Activation

Platelet-activating factor (PAF) is a potent, bioactive phospholipid that acts on multiple cells and tissues through its G protein-coupled receptor (GPCR). PAF is not stored but is rapidly generated via enzymatic acetylation of the precursor 1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine (lysoP...

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Bibliografiske detaljer
Main Authors: Welch, Emily J., Naikawadi, Ram P., Li, Zhenyu, Lin, Phoebe, Ishii, Satoshi, Shimizu, Takao, Tiruppathi, Chinnaswamy, Du, Xiaoping, Subbaiah, Papasani V., Ye, Richard D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646610/
https://ncbi.nlm.nih.gov/pubmed/18931035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051003
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