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New twist on the regulation of NKG2D ligand expression

The NK cell–activating receptor NKG2D plays a prominent role in antitumor immune responses. Expression of the multiple NKG2D ligands must be tightly controlled to guarantee that NK cells attack tumors but not healthy cells. New data reveal a novel mechanism of posttranslational regulation of the mou...

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Hlavní autor: Cerwenka, Adelheid
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646580/
https://ncbi.nlm.nih.gov/pubmed/19204110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090225
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