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Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs
Epithelial–mesenchymal transition (EMT) is required for mesodermal differentiation during development. The zinc-finger transcription factor, Snail1, can trigger EMT and is sufficient to transcriptionally reprogram epithelial cells toward a mesenchymal phenotype during neoplasia and fibrosis. Whether...
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| Glavni autori: | , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646556/ https://ncbi.nlm.nih.gov/pubmed/19188491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810113 |
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